publications

Goodwin A.F., Kim R., Bush J.O. Klein O.D. (2015). From Bench to Bedside and Back: Improving Diagnosis and Treatment of Craniofacial malformations utilizing Animal Models. Current Topics in Developmental Biology. 115: 459-92. Pubmed

Lewis, A.E., Hwa J., Wang R., Soriano P., Bush J. O. (2015). Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature. Developmental Biology, 406(2): 186-95. Pubmed

Kim, S., Lewis, A. E., Singh, V., Ma, X., Adelstein, R. and Bush, J. O. (2015). Convergence and Extrusion Are Required for Normal Fusion of the Mammalian Secondary Palate. PLoS Biol 13(4), e1002122. Pubmed.

Agrawal, P., Wang, M., Kim, S., Lewis, A. E. and Bush, J. O. (2014). Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate. Dev. Dyn. 243, 1470–1476. Pubmed.

Lewis, A., Vasudevan, H., O’Neill, A., Soriano, P., Bush, J.O.* (2013) The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling. Developmental Biology, 379(2):229-34. PubMed.

Arvanitis, D.N., Behar, A., Tryoen-Toth, P., Bush, J.O., Jungas, T., Vitale, N., and Davy A (2013) Ephrin-B1 maintains apical adhesion of neural progenitors. Development 140(10):2082-92. PubMed.

Bush, J.O. and Soriano, P (2012) Eph/ephrin signaling: Genetic, phosphoproteomic, and transcriptomic approaches. Seminars in cell & developmental biology, 23(1):26-34. PubMed

Bush, J.O. and R. Jiang, R.(2011) Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development. Development 139(2): 231-43. PubMed

Bush, J. O. and Soriano, P. (2010). Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries. Genes Dev. 24, 2048-60. PubMed

Bush, J. O. and Soriano, P. (2009). Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 23, 1586-99. COVER IMAGE. PubMed

Chen, J., Bush, J. O., Ovitt, C. E., Lan, Y. and Jiang, R. (2007). The TGF-beta pseudoreceptor gene Bambi is dispensable for mouse embryonic development and postnatal survival. Genesis 45, 482-6. PubMed

Davy, A., Bush, J. O. and Soriano, P. (2006). Inhibition of gap junction communication at ectopic Eph/ephrin boundaries underlies craniofrontonasal syndrome. PLoS Biol. 4, e315. PubMed

Jiang, R., Bush, J. O. and Lidral, A. C. (2006). Development of the upper lip: morphogenetic and molecular mechanisms. Dev Dyn. 235, 1152-66. COVER IMAGE PubMed

Lan, Y., Ryan, R. C., Zhang, Z., Bullard, S. A., Bush, J. O., Maltby, K. M., Lidral, A. C. and Jiang, R. (2006). Expression of Wnt9b and activation of canonical Wnt signaling during midfacial morphogenesis in mice. Dev Dyn. 235, 1448-54. PubMed

Bush, J. O., Lan, Y. and Jiang, R. (2004). The cleft lip and palate defects in Dancer mutant mice result from gain of function of the Tbx10 gene. Proc Natl Acad Sci U S A 101, 7022-7. PubMed

Bush, J. O., Maltby, K. M., Cho, E. S. and Jiang, R. (2003). The T-box gene Tbx10 exhibits a uniquely restricted expression pattern during mouse embryogenesis. Gene Expr Patterns 3, 533-8. PubMed

Bush, J. O., Lan, Y., Maltby, K. M. and Jiang, R. (2002). Isolation and developmental expression analysis of Tbx22, the mouse homolog of the human X-linked cleft palate gene. Dev Dyn. 225, 322-6. PubMed