Bold denotes Bush lab members
*Equal contribution
Corresponding author

25.       Teng T*, Teng CS*, Kaartinen V, Bush JO. A unique form of collective epithelial migration is crucial for tissue fusion in the secondary palate and can overcome loss of epithelial apoptosis. Development. 2022; dev.200181. doi:10.1242/dev.200181 Visit journal; Read PDF
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24.       Bush JO. Cellular and molecular mechanisms of EPH/EPHRIN signaling in evolution and development. Curr Top Dev Biol. 2022;149: 153–201. doi:10.1016/bs.ctdb.2022.02.005 Visit journal; Read PDF

23.       Lewis AE, Kuwahara A, Franzosi J, Bush JO. Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting. Cell Rep. 2022;38: 110510. doi:10.1016/j.celrep.2022.110510 Visit journal; Read PDF

22.       Mincer ST, Niethamer TK, Teng T, Bush JO*, Percival CJ*. Investigating the effects of compound paralogous EPHB receptor mutations on mouse facial development. Dev Dyn. 2022. doi:10.1002/dvdy.454 Visit journal; Read PDF

21.       Kindberg AA, Srivastava V, Muncie JM, Weaver VM, Gartner ZJ, Bush JO. EPH/EPHRIN regulates cellular organization by actomyosin contractility effects on cell contacts. J Cell Biol. 2021;220: e202005216. doi:10.1083/jcb.202005216 Visit journal; Read PDF
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20.       Zhou J, Lin Y, Huynh T, Noguchi H, Bush JO, Pleasure SJ. NMDA receptors control development of somatosensory callosal axonal projections. Elife. 2021;10: e59612. doi:10.7554/eLife.59612 Visit journal; Read PDF

19.       Kuwahara A, Lewis AE, Coombes C, Leung F-S, Percharde M, Bush JO. Delineating the early transcriptional specification of the mammalian trachea and esophagus. Elife. 2020;9: e55526. doi:10.7554/eLife.55526 Visit journal; Read PDF
Read press coverage

18.       Kindberg A, Hu JK, Bush JO. Forced to communicate: Integration of mechanical and biochemical signaling in morphogenesis. Curr Opin Cell Biol. 2020;66: 59–68. doi:10.1016/j.ceb.2020.05.004 Visit journal; Read PDF

17.       Niethamer TK, Teng T, Franco M, Du YX, Percival CJ, Bush JO. Aberrant cell segregation in the craniofacial primordium and the emergence of facial dysmorphology in craniofrontonasal syndrome. PLoS Genet. 2020;16: e1008300. doi:10.1371/journal.pgen.1008300 Visit journal; Read PDF

16.       Goodwin AF, Chen CP, Vo NT, Bush JO, Klein OD. YAP/TAZ Regulate Elevation and Bone Formation of the Mouse Secondary Palate. J Dent Res. 2020;99: 1387–1396. doi:10.1177/0022034520935372 Visit journal; Read PDF

15.       Wall E, Scoles J, Joo A, Klein O, Quinonez C, Bush JO, et al. The UCSF Mouse Inventory Database Application, an Open Source Web App for Sharing Mutant Mice within a Research Community. G3 (Bethesda). 2020. doi:10.1534/g3.120.401086 Visit journal; Read PDF

14.       Bush JO, Andersson ER. Editorial: Signaling pathways instruct the blueprint of life. Dev Biol. 2019;447: 1–2. doi:10.1016/j.ydbio.2018.06.002 Visit journal; Read PDF

13.       Niethamer TK, Bush JO. Getting direction(s): The Eph/ephrin signaling system in cell positioning. Dev Biol. 2019;447: 42–57. doi:10.1016/j.ydbio.2018.01.012 Visit journal; Read PDF

12.       Kindberg AA, Bush JO. Cellular organization and boundary formation in craniofacial development. Genesis. 2019;57: e23271. doi:10.1002/dvg.23271 Visit journal; Read PDF

11.       Niethamer TK, Larson AR, O’Neill AK, Bershteyn M, Hsiao EC, Klein OD, Pomerantz JH, Bush JO. EPHRIN-B1 Mosaicism Drives Cell Segregation in Craniofrontonasal Syndrome hiPSC-Derived Neuroepithelial Cells. Stem Cell Reports. 2017;8: 529–537. doi:10.1016/j.stemcr.2017.01.017 Visit journal; Read PDF

10.       Kim S, Prochazka J, Bush JO. Live Imaging of Mouse Secondary Palate Fusion. J Vis Exp. 2017. doi:10.3791/56041 Visit journal; Read PDF

9.         O’Neill AK, Kindberg AA, Niethamer TK, Larson AR, Ho H-YH, Greenberg ME, Bush JO. Unidirectional Eph/ephrin signaling creates a cortical actomyosin differential to drive cell segregation. J Cell Biol. 2016;215: 217–229. doi:10.1083/jcb.201604097 Visit journal; Read PDF

8.         Kim S, Lewis AE, Singh V, Ma X, Adelstein R, Bush JO. Convergence and extrusion are required for normal fusion of the mammalian secondary palate. PLoS Biol. 2015;13: e1002122. doi:10.1371/journal.pbio.1002122 Visit journal; Read PDF

7.         Lewis AE, Hwa J, Wang R, Soriano P, Bush JO. Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature. Dev Biol. 2015;406: 186–195. doi:10.1016/j.ydbio.2015.08.021 Visit journal; Read PDF

6.         Goodwin AF, Kim R, Bush JO*, Klein OD*. From Bench to Bedside and Back: Improving Diagnosis and Treatment of Craniofacial Malformations Utilizing Animal Models. Curr Top Dev Biol. 2015;115: 459–492. doi:10.1016/bs.ctdb.2015.07.003 Visit journal; Read PDF

5.         Agrawal P, Wang M, Kim S, Lewis AE, Bush JO. Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate. Dev Dyn. 2014;243: 1470–1476. doi:10.1002/dvdy.24170 Visit journal; Read PDF

4.         Arvanitis DN, Béhar A, Tryoen-Tóth P, Bush JO, Jungas T, Vitale N, et al. Ephrin B1 maintains apical adhesion of neural progenitors. Development. 2013;140: 2082–2092. doi:10.1242/dev.088203 Visit journal; Read PDF

3.         Lewis AE, Vasudevan HN, O’Neill AK, Soriano P, Bush JO. The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling. Dev Biol. 2013;379: 229–234. doi:10.1016/j.ydbio.2013.04.026 Visit journal; Read PDF

2.         Bush JO, Jiang R. Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development. Development. 2012;139: 231–243. doi:10.1242/dev.067082 Visit journal; Read PDF

1.         Bush JO, Soriano P. Eph/ephrin signaling: genetic, phosphoproteomic, and transcriptomic approaches. Semin Cell Dev Biol. 2012;23: 26–34. doi:10.1016/j.semcdb.2011.10.018 Visit journal; Read PDF

Selected papers from before

4.         Bush JO, Soriano P. Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries. Genes Dev. 2010;24: 2068–80. doi:10.1101/gad.1963210 Visit journal; Read PDF

3.         Bush JO, Soriano P. Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009;23: 1586–99. doi:10.1101/gad.1807209 Visit journal; Read PDF

2.         Jiang R, Bush JO, Lidral AC. Development of the upper lip: Morphogenetic and molecular mechanisms. Dev Dyn. 2006;235: 1152–1166. doi:10.1002/dvdy.20646 Visit journal; Read PDF

1.         Bush JO, Lan Y, Jiang R. The cleft lip and palate defects in Dancer mutant mice result from gain of function of the Tbx10 gene. Proc Natl Acad Sci U S A. 2004;101: 7022–7. doi:10.1073/pnas.0401025101 Visit journal; Read PDF